R8Q (p.Arg8Gln) variant of CDK7 (Cyclin-dependent kinase 7)
R8Q (p.Arg8Gln) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
R8Q (p.Arg8Gln) variant details
- p.Arg8Gln
- gnomAD 5-69234998-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.11
- CADD 24.00
- PolyPhen-2 0.22
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available