R8L (p.Arg8Leu) variant of CDK7 (Cyclin-dependent kinase 7)
R8L (p.Arg8Leu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
R8L (p.Arg8Leu) variant details
- p.Arg8Leu
- gnomAD 5-69234998-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.20
- CADD 24.00
- PolyPhen-2 0.26
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available