R30K (p.Arg30Lys) variant of CDK7 (Cyclin-dependent kinase 7)
R30K (p.Arg30Lys) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R30K (p.Arg30Lys) variant details
- p.Arg30Lys
- gnomAD rs1245007515
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.05
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the HGDP:HAN population (allele frequency 0.015)
- Structural context available