R11H (p.Arg11His) variant of CDK7 (Cyclin-dependent kinase 7)
R11H (p.Arg11His) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
R11H (p.Arg11His) variant details
- p.Arg11His
- 1000Genomes rs555422765
- ExAC rs555422765
- TOPMed rs555422765
- gnomAD rs555422765
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.30
- CADD 32.00
- PolyPhen-2 0.76
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available