Q36R (p.Gln36Arg) variant of CDK7 (Cyclin-dependent kinase 7)
Q36R (p.Gln36Arg) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Q36R (p.Gln36Arg) variant details
- p.Gln36Arg
- ExAC rs779716833
- TOPMed rs779716833
- gnomAD rs779716833
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.04
- CADD 21.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available