Q22* (p.Gln22Ter) variant of CDK7 (Cyclin-dependent kinase 7)
Q22* (p.Gln22Ter) in CDK7 (Cyclin-dependent kinase 7) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
Q22* (p.Gln22Ter) variant details
- p.Gln22Ter
- ExAC rs761944819
- gnomAD rs761944819
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.85
- CADD 44.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available