L45L (p.Leu45Leu) variant of CDK7 (Cyclin-dependent kinase 7)
L45L (p.Leu45Leu) in CDK7 (Cyclin-dependent kinase 7) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L45L (p.Leu45Leu) variant details
- p.Leu45Leu
- gnomAD 5-69252426-T-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.264
- CADD 11.90
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available