L15Q (p.Leu15Gln) variant of CDK7 (Cyclin-dependent kinase 7)
L15Q (p.Leu15Gln) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
L15Q (p.Leu15Gln) variant details
- p.Leu15Gln
- gnomAD 5-69235019-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.27
- CADD 25.50
- PolyPhen-2 0.90
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available