L15M (p.Leu15Met) variant of CDK7 (Cyclin-dependent kinase 7)
L15M (p.Leu15Met) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L15M (p.Leu15Met) variant details
- p.Leu15Met
- gnomAD 5-69235018-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.15
- CADD 23.90
- PolyPhen-2 0.76
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available