K6T (p.Lys6Thr) variant of CDK7 (Cyclin-dependent kinase 7)
K6T (p.Lys6Thr) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K6T (p.Lys6Thr) variant details
- p.Lys6Thr
- gnomAD rs1196381635
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.18
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available