K6R (p.Lys6Arg) variant of CDK7 (Cyclin-dependent kinase 7)
K6R (p.Lys6Arg) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
K6R (p.Lys6Arg) variant details
- p.Lys6Arg
- gnomAD 5-69234992-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.05
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available