K6E (p.Lys6Glu) variant of CDK7 (Cyclin-dependent kinase 7)
K6E (p.Lys6Glu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K6E (p.Lys6Glu) variant details
- p.Lys6Glu
- gnomAD 5-69234991-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.18
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available