K32E (p.Lys32Glu) variant of CDK7 (Cyclin-dependent kinase 7)
K32E (p.Lys32Glu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
K32E (p.Lys32Glu) variant details
- p.Lys32Glu
- gnomAD 5-69235421-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.25
- CADD 22.60
- PolyPhen-2 0.06
- SIFT 0.83
- Population evidence available
- Structural context available
- Literature evidence available