K28N (p.Lys28Asn) variant of CDK7 (Cyclin-dependent kinase 7)
K28N (p.Lys28Asn) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K28N (p.Lys28Asn) variant details
- p.Lys28Asn
- gnomAD 5-69235411-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.51
- CADD 29.60
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available