K14E (p.Lys14Glu) variant of CDK7 (Cyclin-dependent kinase 7)
K14E (p.Lys14Glu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K14E (p.Lys14Glu) variant details
- p.Lys14Glu
- gnomAD 5-69235015-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.32
- CADD 31.00
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available