K10R (p.Lys10Arg) variant of CDK7 (Cyclin-dependent kinase 7)
K10R (p.Lys10Arg) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
K10R (p.Lys10Arg) variant details
- p.Lys10Arg
- gnomAD rs1180242079
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.04
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available