K10E (p.Lys10Glu) variant of CDK7 (Cyclin-dependent kinase 7)
K10E (p.Lys10Glu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K10E (p.Lys10Glu) variant details
- p.Lys10Glu
- gnomAD 5-69235003-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.19
- CADD 23.50
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available