I37V (p.Ile37Val) variant of CDK7 (Cyclin-dependent kinase 7)
I37V (p.Ile37Val) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I37V (p.Ile37Val) variant details
- p.Ile37Val
- ExAC rs748896779
- TOPMed rs748896779
- gnomAD rs748896779
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.15
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.23
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available