I37T (p.Ile37Thr) variant of CDK7 (Cyclin-dependent kinase 7)
I37T (p.Ile37Thr) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
I37T (p.Ile37Thr) variant details
- p.Ile37Thr
- ExAC rs755309372
- TOPMed rs755309372
- gnomAD rs755309372
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.31
- CADD 24.70
- PolyPhen-2 0.92
- SIFT 0.50
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available