I37M (p.Ile37Met) variant of CDK7 (Cyclin-dependent kinase 7)
I37M (p.Ile37Met) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
I37M (p.Ile37Met) variant details
- p.Ile37Met
- gnomAD 5-69235438-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.28
- CADD 11.70
- PolyPhen-2 0.43
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available