I37L (p.Ile37Leu) variant of CDK7 (Cyclin-dependent kinase 7)
I37L (p.Ile37Leu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
I37L (p.Ile37Leu) variant details
- p.Ile37Leu
- gnomAD 5-69235436-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.24
- CADD 23.20
- PolyPhen-2 0.06
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available