I37F (p.Ile37Phe) variant of CDK7 (Cyclin-dependent kinase 7)
I37F (p.Ile37Phe) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
I37F (p.Ile37Phe) variant details
- p.Ile37Phe
- ExAC rs748896779
- TOPMed rs748896779
- gnomAD rs748896779
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.34
- CADD 23.40
- PolyPhen-2 0.12
- SIFT 0.28
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available