G46R (p.Gly46Arg) variant of CDK7 (Cyclin-dependent kinase 7)
G46R (p.Gly46Arg) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
G46R (p.Gly46Arg) variant details
- p.Gly46Arg
- gnomAD 5-69252427-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- REVEL 0.48
- CADD 34.00
- PolyPhen-2 0.70
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available