D4E (p.Asp4Glu) variant of CDK7 (Cyclin-dependent kinase 7)
D4E (p.Asp4Glu) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
D4E (p.Asp4Glu) variant details
- p.Asp4Glu
- gnomAD 5-69234987-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.12
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available