D31G (p.Asp31Gly) variant of CDK7 (Cyclin-dependent kinase 7)
D31G (p.Asp31Gly) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
D31G (p.Asp31Gly) variant details
- p.Asp31Gly
- gnomAD 5-69235419-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.72
- REVEL 0.72
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available