Y77C (p.Tyr77Cys) variant of CDK1 (Cyclin-dependent kinase 1)
Y77C (p.Tyr77Cys) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
Y77C (p.Tyr77Cys) variant details
- p.Tyr77Cys
- gnomAD 10-60785699-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.70
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available