Y15H (p.Tyr15His) variant of CDK1 (Cyclin-dependent kinase 1)
Y15H (p.Tyr15His) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
Y15H (p.Tyr15His) variant details
- p.Tyr15His
- gnomAD 10-60784710-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.602
- REVEL 0.55
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available