V44F (p.Val44Phe) variant of CDK1 (Cyclin-dependent kinase 1)
V44F (p.Val44Phe) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
V44F (p.Val44Phe) variant details
- p.Val44Phe
- gnomAD 10-60784797-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.46
- CADD 27.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available