T14S (p.Thr14Ser) variant of CDK1 (Cyclin-dependent kinase 1)
T14S (p.Thr14Ser) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
T14S (p.Thr14Ser) variant details
- p.Thr14Ser
- TOPMed rs1201393937
- gnomAD rs1201393937
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.36
- CADD 25.50
- PolyPhen-2 0.47
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available