R59H (p.Arg59His) variant of CDK1 (Cyclin-dependent kinase 1)
R59H (p.Arg59His) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R59H (p.Arg59His) variant details
- p.Arg59His
- cosmic curated COSV57348
- ExAC rs773501650
- gnomAD rs773501650
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.06
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available