R59C (p.Arg59Cys) variant of CDK1 (Cyclin-dependent kinase 1)
R59C (p.Arg59Cys) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R59C (p.Arg59Cys) variant details
- p.Arg59Cys
- cosmic curated COSV10035
- ESP rs8755
- ExAC rs8755
- TOPMed rs8755
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- REVEL 0.21
- CADD 32.00
- PolyPhen-2 0.51
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 0.00075)
- Structural context available