P45A (p.Pro45Ala) variant of CDK1 (Cyclin-dependent kinase 1)
P45A (p.Pro45Ala) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
P45A (p.Pro45Ala) variant details
- p.Pro45Ala
- gnomAD 10-60784800-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- REVEL 0.43
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available