L70I (p.Leu70Ile) variant of CDK1 (Cyclin-dependent kinase 1)
L70I (p.Leu70Ile) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
L70I (p.Leu70Ile) variant details
- p.Leu70Ile
- gnomAD 10-60785677-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.29
- CADD 21.10
- PolyPhen-2 0.05
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available