L70H (p.Leu70His) variant of CDK1 (Cyclin-dependent kinase 1)
L70H (p.Leu70His) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
L70H (p.Leu70His) variant details
- p.Leu70His
- gnomAD 10-60785678-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- REVEL 0.55
- CADD 29.70
- PolyPhen-2 0.98
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available