L66F (p.Leu66Phe) variant of CDK1 (Cyclin-dependent kinase 1)
L66F (p.Leu66Phe) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
L66F (p.Leu66Phe) variant details
- p.Leu66Phe
- cosmic curated COSV10035
- gnomAD rs1460089100
- Missense
- Variant Prioritization Score for Impact Estimate 0.727
- REVEL 0.65
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available