I49V (p.Ile49Val) variant of CDK1 (Cyclin-dependent kinase 1)
I49V (p.Ile49Val) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I49V (p.Ile49Val) variant details
- p.Ile49Val
- ESP rs142650572
- ExAC rs142650572
- TOPMed rs142650572
- gnomAD rs142650572
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.05
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available