I10M (p.Ile10Met) variant of CDK1 (Cyclin-dependent kinase 1)
I10M (p.Ile10Met) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
I10M (p.Ile10Met) variant details
- p.Ile10Met
- gnomAD rs1179034229
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.40
- CADD 25.90
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available