E8G (p.Glu8Gly) variant of CDK1 (Cyclin-dependent kinase 1)
E8G (p.Glu8Gly) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
E8G (p.Glu8Gly) variant details
- p.Glu8Gly
- gnomAD 10-60780188-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.36
- CADD 32.00
- PolyPhen-2 0.53
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.8e-07)
- Structural context available
- Literature evidence available