E57Q (p.Glu57Gln) variant of CDK1 (Cyclin-dependent kinase 1)
E57Q (p.Glu57Gln) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
E57Q (p.Glu57Gln) variant details
- p.Glu57Gln
- gnomAD rs1230964680
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.44
- CADD 27.90
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available