E40K (p.Glu40Lys) variant of CDK1 (Cyclin-dependent kinase 1)
E40K (p.Glu40Lys) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
E40K (p.Glu40Lys) variant details
- p.Glu40Lys
- ExAC rs746720738
- gnomAD rs746720738
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.43
- CADD 29.80
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available