E40D (p.Glu40Asp) variant of CDK1 (Cyclin-dependent kinase 1)
E40D (p.Glu40Asp) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
E40D (p.Glu40Asp) variant details
- p.Glu40Asp
- gnomAD 10-60784787-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.11
- CADD 21.40
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available