E12K (p.Glu12Lys) variant of CDK1 (Cyclin-dependent kinase 1)
E12K (p.Glu12Lys) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
E12K (p.Glu12Lys) variant details
- p.Glu12Lys
- gnomAD 10-60780199-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.631
- REVEL 0.49
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available