D68E (p.Asp68Glu) variant of CDK1 (Cyclin-dependent kinase 1)
D68E (p.Asp68Glu) in CDK1 (Cyclin-dependent kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
D68E (p.Asp68Glu) variant details
- p.Asp68Glu
- ExAC rs768316764
- gnomAD rs768316764
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.10
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available