V44F (p.Val44Phe) variant of CDH2 (Cadherin-2)
V44F (p.Val44Phe) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V44F (p.Val44Phe) variant details
- p.Val44Phe
- gnomAD rs1246347582
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.17
- MetaLR 0.12
- MetaSVM -1.05
- CADD 23.20
- PolyPhen-2 0.60
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available