V23L (p.Val23Leu) variant of CDH2 (Cadherin-2)
V23L (p.Val23Leu) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V23L (p.Val23Leu) variant details
- p.Val23Leu
- ExAC rs755151089
- gnomAD rs755151089
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.11
- MetaLR 0.06
- MetaSVM -1.08
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 0.60
- Population evidence available
- Structural context available