S26F (p.Ser26Phe) variant of CDH2 (Cadherin-2)
S26F (p.Ser26Phe) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S26F (p.Ser26Phe) variant details
- p.Ser26Phe
- ExAC rs766647206
- gnomAD rs766647206
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.15
- MetaLR 0.08
- MetaSVM -1.06
- CADD 24.30
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available