R3G (p.Arg3Gly) variant of CDH2 (Cadherin-2)
R3G (p.Arg3Gly) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R3G (p.Arg3Gly) variant details
- p.Arg3Gly
- ExAC rs761151029
- TOPMed rs761151029
- gnomAD rs761151029
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.28
- MetaLR 0.09
- MetaSVM -1.00
- CADD 24.70
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available