N57S (p.Asn57Ser) variant of CDH2 (Cadherin-2)
N57S (p.Asn57Ser) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N57S (p.Asn57Ser) variant details
- p.Asn57Ser
- TOPMed rs1459488007
- gnomAD rs1459488007
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.09
- MetaLR 0.10
- MetaSVM -1.05
- CADD 23.00
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available