K109R (p.Lys109Arg) variant of CDH2 (Cadherin-2)
K109R (p.Lys109Arg) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K109R (p.Lys109Arg) variant details
- p.Lys109Arg
- gnomAD rs1429699775
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.03
- CADD 17.70
- PolyPhen-2 0.04
- SIFT 0.57
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available