K101R (p.Lys101Arg) variant of CDH2 (Cadherin-2)
K101R (p.Lys101Arg) in CDH2 (Cadherin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K101R (p.Lys101Arg) variant details
- p.Lys101Arg
- gnomAD rs750207054
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.05
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available